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TMA survival analysis

Tom Bahar and Ido Raizman

Supervised by Arkadi Piven and Gill Shamai

Abstract

Survival analysis in breast cancer is crucial for personalizing treatment, and deep
learning models applied to histology images offer a promising avenue for improving
prognostic predictions. Tissue Microarrays (TMAs) provide a high-throughput
method for analyzing large patient cohorts, making them a natural data source for
training such models. In this work, we adopt a pipeline architecture using the pre-
trained Titan foundation model to encode entire TMA slides, which are then fed into
a regression head to predict a patient-specific risk score. Our findings demonstrate
that this approach can effectively stratify patients into distinct prognostic groups,
achieving a Concordance Index of 0.6175 on the BCOU dataset. The outcomes are
competitive with other TMA-based models.

Project Report

Please, see project report.

Final Presentation

Please, see final presentation.

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